UWinChem

Wednesday, January 17, 2018

Seminar: Caleb Martin (Baylor University) - Friday, Jan. 19, 2018 @ 3:00 p.m.

Seminar: Caleb Martin (Baylor University)

UWinChemBiochem Seminar Series - Winter 2018

Caleb Martin
Department of Chemistry and Biochemistry
Baylor University, Waco, TX
Title: “Exploiting the Diverse Chemistry of Boroles to Access Unsaturated Boracycles”
Web: http://sites.baylor.edu/caleb_d_martin/

Friday, Jan. 19, 2018 @ 3:00 p.m.
Room #186 Essex Hall

**Everyone Welcome**


Friday, January 12, 2018

Seminar: Jeff Reimer (University of California at Berkeley) - Tuesday, Jan. 16, 2018 @ 3:00 p.m.

Seminar: Jeff Reimer (University of California at Berkeley)

UWinChemBiochem Seminar Series - Winter 2018

Jeff Reimer
Department of Chemistry
University of California at Berkeley 
Title: “Why, and How, I would like to Decarbonize our Air”
Web: https://chemistry.berkeley.edu/faculty/cbe/reimer

Tuesday, Jan. 16, 2018 @ 3:00 p.m.
Room #109 Essex Hall

**Everyone Welcome**
**Note the special room***



Tuesday, January 9, 2018

Summer Research for Undergrads! NSERC USRA Applications Due Jan. 22, 2018

Summer Research for Undergrads!  NSERC USRA Applications Due Jan. 22, 2018

NSERC – USRA SCHOLARSHIPS

DEPARTMENT OF CHEMISTRY & BIOCHEMISTRY DEADLINE – MONDAY, JANUARY 22, 2018

- Official transcripts required (Wait until January to request one so the Fall grades appear)

- All printed application material must be submitted to Marlene Bezaire, room #273-1 Essex Hall no later that Monday, January 22, 2018

For more information, please click here!

or visit: http://www1.uwindsor.ca/chemistry/summer-research




Sunday, January 7, 2018

Seminar: Andre Simpson (Department of Chemistry, University of Toronto, Canada) - Friday, Jan. 12, 2018 @ 3:00 p.m.

Seminar: Andre Simpson  (Department of Chemistry, University of Toronto, Canada)


UWinChemBiochem Seminar Series - Winter 2018
André J. Simpson
Friday, Jan. 12, 2018 @ 3:00 p.m.
**Everyone Welcome**


Department of Chemistry
University of Toronto 
Title: “From Structure to Interactions to In vivo NMR: The vast potential of NMR Spectroscopy in Environmental Research”
Web: http://www.utsc.utoronto.ca/~asimpson/

Room #186 Essex Hall







Abstract:


NMR spectroscopy is arguably the most powerful tool for elucidating structures and probing molecular interactions. Practically all environmental research, at least to some extent, involves working with ultra-complex natural mixtures that are ubiquitous in soil, water, and air. NMR can provide information not only as to the basic chemical structures present in a mixture, but can potentially provide information as to the self-associations of molecules (aggregation and flocculation processes), their mechanistic interactions with xenobiotics (transport of contaminants) and provide the direct connection between molecular scale processes (environments of individual nuclei) and macroscopic scale (visual), in the form NMR imaging. 

This presentation will take the audience through an evolution of my career from molecular-structure at one extreme to the impact of chemicals in living systems at the other.

Structure: Understanding the structure of soils, air particles, and dissolved organic is a critical precursor to understanding how these materials function. This information is desperately needed to develop the most efficient soil remediation and agricultural practices as-well as better predict carbon sequestration and climate change.

Interactions: With a better understanding as to the structural components and NMR assignments for key environmental matrices it is then possible to determine, how, where, and why contaminants get sequestered and are challenging to remediate. A range of novel NMR experiments will be introduced along with a new technology termed comprehensive multi-phase NMR. Comprehensive Multiphase (CMP) NMR, was co-developed between my group and Bruker Biospin. The approach combines all the electronics from solution-state, semi-solid and solid-state NMR into a single NMR probe. The resulting technology permits an uncompromised analysis of liquid, semi-solid and solid components within unaltered samples in their natural swollen state. As well as unravelling the binding orientation, and receptors for contaminants/drugs CMP-NMR is also capable of monitoring the kinetic transfer between and across interfaces providing an unprecedented window into otherwise inaccessible molecular information.

Impact: With an understanding as to “what soil is?” and “which chemical components bind contaminants?" the key questions become “what does it all mean?” and “how are living systems impacted?”. For example, if a herbicide is bound tightly to the protein fraction of soil is it still bioavailable? Would this still hold true with climate change or change in land use? An even more challenging but important question is “out of the 100’s or 1000’s chemicals we are exposed to everyday which ones truly impacts our health?” Indeed similar questions are asked everyday by policy makers. NMR has great potential to address such challenges when employed as the “molecular interpreter” of living systems under environmental stress. In this final section in-vivo NMR is introduced on small invertebrates. Static studies (i.e. using a flow system and solution-state probes) provide a low stress environment to study metabolic flux in response to stressors. Conversely, CMP-NMR, can potentially be used to study and differentiate different phases (liquids (metabolites), gels (proteins, membranes), solids (shell, bone)) in-vivo. A wide range of novel experiments will be introduced that greatly improve the depth and breadth of information that can be obtained from NMR of living systems. Combined the approaches hold the potential to identify which are the most potent environmental stressors in complex natural samples, explain their toxic-mode-of-action and even act as early warning system to identify environmental stress, prior to disease, or ecosystem shifts. 




         

Wednesday, January 3, 2018

You should hire an undergrad for your lab - by Prof. John Trant

You should hire an undergrad for your lab
Undergraduate colleagues make you a better researcher and teacher. Here’s how.
By JOHN TRANT | DEC 29 2017

Read Prof. John Trant's article at the University Affairs web site!

https://www.universityaffairs.ca/opinion/in-my-opinion/hire-undergrad-lab/




Seminar: Amy Szuchmacher Blum (McGill University) - Friday, Jan. 5, 2018 @ 3:00 p.m.

Seminar: Amy Szuchmacher Blum (McGill University)

UWinChemBiochem Seminar Series - Winter 2018

Amy Szuchmacher Blum
Department of Chemistry
McGill University
Title: “Making viruses work for us: self-assembled nanostructured materials”
Web: http://www.mcgill.ca/chemistry/faculty/amy-blum

Friday, Jan. 5, 2018 @ 3:00 p.m.
Room #186 Essex Hall

**Everyone Welcome**



Wednesday, December 20, 2017

Membranes Best Paper Award 2017 - to Prof. Drew Marquardt


Membranes Best Paper Award 2017 - to Prof. Drew Marquardt

Drew Marquardt’s paper titled "Asymmetric Lipid Membranes: Towards More Realistic Model Systems" was selected as the first prize of the Membranes Best Paper Award.


From: Membranes 2015, 5, 180-196

For more information on Prof. Marquardt's research, click here!