UWinChemBiochem Seminar Series - Fall 2017
Prof. Tony Durst
Department of Chemistry and Biomolecular Sciences
University of Ottawa
Title: Prospecting for Natural Products in Costa Rica
Friday, October 27, 2017 @ 3:00 p.m.
Room #186 Essex Hall
**Everyone Welcome**
Abstract:
Our twenty five year long collaboration with botanists in Costa Rica has given us access to the vast plant biodiversity of Costa Rica. Joint work John Arnason (Biology) and Zul Merali (Psychology) at the University of Ottawa to enabled us to isolate novel chemical compounds and discover new applications of known entities. The seminar will focus on the development of new CYP450 inhibitors as potential insecticide synergists emanating from dillapiol isolated from Piper aduncum and the discovery of the anti-anxiety principle in Souroubea sympetala, a relatively rare Costa Rican vine. The latter work has led to a commercial product for the treatment of noise related anxiety in dogs. This product has shown excellent results in an animal model for the treatment of Post-Traumatic Stress. Health Canada approved Human Safety trials will be carried out shortly.
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